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Peptic ulcer disease Generics
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Aluminium Hydroxide
N/A
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Magaldrate + Simethicone Chewable
N/A
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Metronidazole
Antimicrobial Drugs
...
Misoprostol
Genitourinary System Drugs
...
Nizatidine
N/A
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Omeprazole
Gastrointestinal System Drugs
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Omeprazole 20mg + Sodium bicarbonate 1100mg
N/A
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Oxyphencyclimine Hydrochloride
N/A
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Oxyphenonium Bromide
Gastrointestinal System Drugs
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Pantoprazole Sodium Sesquihydrate
Gastrointestinal System Drugs
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Propantheline Bromide
Gastrointestinal System Drugs
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Rabeprazole Sodium
Gastrointestinal System Drugs
...
Ranitidine Hydrochloride
Gastrointestinal System Drugs
...
Roxatidine
N/A
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Sodium Alginate + Sodium Bicarbonate + Calcium Car...
Gastrointestinal System Drugs
...
Magaldrate + Simethicone
Gastrointestinal System Drugs
...
Magaldrate
Gastrointestinal System Drugs
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Aluminium Hydroxide + Magnesium Trisilicate
N/A

Peptic ulcer disease - Generics

Peptic ulcer disease (PUD) is a condition characterized by sores or ulcers that develop on the lining of the stomach, esophagus, or duodenum (the first part of the small intestine). The most common cause of PUD is infection with the bacterium Helicobacter pylori (H. pylori), although prolonged use of nonsteroidal anti-inflammatory drugs (NSAIDs) and excessive alcohol consumption can also contribute to the development of ulcers.

Symptoms of PUD can include abdominal pain or discomfort, nausea, vomiting, bloating, loss of appetite, and weight loss. These symptoms may be worse on an empty stomach and improve with eating. In severe cases, PUD can cause complications such as bleeding, perforation (a hole in the wall of the stomach or duodenum), or obstruction (blockage of the digestive tract).

Diagnosis of PUD typically involves an upper endoscopy, in which a thin, flexible tube with a camera is inserted through the mouth and down into the stomach and duodenum to examine the ulcers and take tissue samples for biopsy. Other tests, such as a breath test for H. pylori or blood tests to measure stomach acid levels, may also be performed.

Treatment of PUD usually involves a combination of medications and lifestyle modifications. Antibiotics are used to treat H. pylori infection, and acid-suppressing drugs, such as proton pump inhibitors (PPIs) or H2 blockers, can help to reduce the amount of acid in the stomach and promote healing of the ulcers. In cases where NSAID use is the cause of the ulcers, switching to a different medication or reducing the dosage may be necessary. Lifestyle modifications, such as avoiding tobacco and alcohol and eating smaller, more frequent meals, may also be recommended.

With appropriate treatment, most people with PUD can expect a complete recovery. However, long-term follow-up may be necessary to monitor for recurrent ulcers or complications.


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