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Hypercholesterolaemia Generics
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Alirocumab
N/A
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Rosuvastatin
Cardiovascular System Drugs
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Pitavastatin Calcium
Cardiovascular System Drugs
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Niacin (Nicotinic Acid)
Vitamin, Mineral & Nutritional Deficiency
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Gemfibrozil
Cardiovascular System Drugs
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Fluvastatin
Cardiovascular System Drugs
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Fenofibrate
Cardiovascular System Drugs
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Ezetimibe
Cardiovascular System Drugs
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Evolocumab
N/A
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Colesevelam
N/A
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Cholestyramine
N/A
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Bempedoic acid
N/A
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Atorvastatin + Ezetimibe
N/A
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Atorvastatin
N/A
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Simvastatin + Ezetimibe
N/A

Hypercholesterolaemia - Generics

Hypercholesterolemia is a medical condition characterized by high levels of cholesterol in the blood. Cholesterol is a type of fat that is produced by the liver and is found in certain foods. It plays an important role in the body as a building block for cell membranes, hormones, and other vital substances. However, too much cholesterol in the blood can lead to health problems, including an increased risk of heart disease and stroke.

There are two main types of cholesterol: low-density lipoprotein (LDL) and high-density lipoprotein (HDL). LDL cholesterol is often referred to as "bad" cholesterol because it can build up in the walls of arteries, leading to atherosclerosis (hardening of the arteries) and an increased risk of heart disease and stroke. HDL cholesterol, on the other hand, is often referred to as "good" cholesterol because it helps to remove LDL cholesterol from the blood.

Hypercholesterolemia is often asymptomatic, meaning it does not cause any noticeable symptoms. However, over time, high levels of cholesterol can cause the buildup of fatty deposits in the arteries, which can narrow the arteries and reduce blood flow to the heart and brain. This can lead to a range of serious health problems, including:

  • Coronary artery disease: This occurs when the arteries that supply blood to the heart become narrow or blocked, leading to chest pain (angina), heart attack, and other heart problems.
  • Peripheral artery disease: This occurs when the arteries that supply blood to the legs become narrow or blocked, leading to pain and cramping in the legs, especially during exercise.
  • Stroke: This occurs when the blood supply to the brain is interrupted, leading to damage to brain tissue and other serious complications.
  • Aortic aneurysm: This occurs when the walls of the aorta (the largest artery in the body) weaken and bulge, increasing the risk of rupture and internal bleeding.

Hypercholesterolemia can be caused by a variety of factors, including genetics, diet, lifestyle, and certain medical conditions. Some people may have a genetic predisposition to high cholesterol levels, while others may develop hypercholesterolemia as a result of a diet high in saturated and trans fats, lack of physical activity, smoking, and excessive alcohol consumption. Certain medical conditions, such as hypothyroidism, liver disease, and kidney disease, can also contribute to high cholesterol levels.

Treatment for hypercholesterolemia typically involves lifestyle changes and medication. Lifestyle changes may include eating a healthy diet, exercising regularly, quitting smoking, and limiting alcohol consumption. Medications may include statins (which lower LDL cholesterol levels), bile acid sequestrants (which bind to cholesterol in the intestines and prevent it from being absorbed into the bloodstream), and other drugs that help to lower cholesterol levels.

Prevention of hypercholesterolemia involves making healthy lifestyle choices, such as maintaining a healthy weight, eating a healthy diet, exercising regularly, not smoking, and limiting alcohol consumption. Regular cholesterol screenings can also help to detect high cholesterol levels early, before serious health problems occur.


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