“May all be happy, may all be healed, may all be at peace and may no one ever suffer."
Acute promyelocytic leukemia (APL) is a rare and aggressive type of blood cancer that affects the bone marrow and blood cells. APL is caused by the rapid growth and accumulation of immature white blood cells, known as promyelocytes, which can interfere with the production of normal blood cells.
Symptoms of APL can include fatigue, weakness, fever, frequent infections, easy bruising or bleeding, bone pain, and swollen lymph nodes. APL can also cause bleeding disorders, such as disseminated intravascular coagulation (DIC), which can lead to serious complications if not treated promptly.
Treatment for APL typically involves a combination of chemotherapy and a medication called all-trans retinoic acid (ATRA), which helps to induce the maturation of the immature white blood cells. In some cases, additional medications, radiation therapy, or stem cell transplantation may also be used.
The outlook for people with APL has improved significantly in recent years, with many people achieving complete remission and long-term survival. However, APL can be a serious and life-threatening illness if not treated promptly and aggressively.
If you have been diagnosed with APL, it is important to work closely with your healthcare team to develop an appropriate treatment plan. They can help you understand your options, manage any side effects of treatment, and provide support throughout your cancer journey.