“May all be happy, may all be healed, may all be at peace and may no one ever suffer."
Mannitol is a clear, almost colorless and sterile solution of Mannitol. Each 100 ml of Mannitol contains Mannitol BP 20 g. Administered parenterally, Mannitol raises the osmotic pressure of the plasma, thus drawing water out of body tissues and produces an osmotic diuresis. Mannitol is principally used by IV infusion as an osmotic diuretic to preserve renal function in acute renal failure and to reduce raised intracranial and intraocular pressure. Mannitol is also used as an irrigating solution to prevent hemolysis and hemoglobin buildup during transurethral prostatic resection. It is useful in the management of acute drug poisoning where a route of elimination is through kidney. Besides these, it is also used in symptomatic relief of edema, reperfusion injury, termination of pregnancy, and bowel preparation.