“May all be happy, may all be healed, may all be at peace and may no one ever suffer."
Common variable immunodeficiency (CVID) is a rare, primary immunodeficiency disorder characterized by low levels of immunoglobulins (antibodies) in the blood, leading to recurrent bacterial infections, particularly in the respiratory and gastrointestinal tracts. CVID usually manifests in adulthood, but it can also occur in children. The exact cause of CVID is unknown, but it is believed to involve both genetic and environmental factors. Diagnosis is typically based on blood tests that show low levels of immunoglobulins, as well as an assessment of clinical symptoms. Treatment often involves regular infusions of immunoglobulin replacement therapy to help prevent infections and manage symptoms. Antibiotics, antiviral medications, and other treatments may be used to manage infections as they occur.
In the vast majority of CVID cases, the cause is unknown. In around 10% of people with CVID, a genetic mutation has been identified. Researchers believe that the condition is caused by a combination of both environmental and genetic factors. As of now, the environmental factors are unclear.