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Botulism is a rare but serious illness caused by a toxin produced by the bacterium Clostridium botulinum. It can be contracted through contaminated food, wound infections, or inhaling the toxin. Symptoms of botulism can include weakness, dizziness, double vision, difficulty speaking or swallowing, and paralysis. If left untreated, botulism can lead to respiratory failure and death. Treatment for botulism may include administration of an antitoxin to neutralize the toxin, respiratory support to manage breathing difficulties, and antibiotics to treat any associated infections. Prevention measures, such as proper food handling and preparation, and wound care can help reduce the risk of botulism.
The source of foodborne botulism is often home-canned foods that are low in acid, such as fruits, vegetables and fish. However, the disease has also occurred from spicy peppers (chiles), foil-wrapped baked potatoes and oil infused with garlic.
When you eat food containing the toxin, it disrupts nerve function, causing paralysis.
When C. botulinum bacteria get into a wound — possibly caused by an injury you might not notice — they can multiply and produce toxin. Wound botulism has increased in recent decades in people who inject heroin, which can contain spores of the bacteria. In fact, this type of botulism is more common in people who inject black tar heroin.
Babies get infant botulism after consuming spores of the bacteria, which then grow and multiply in their intestinal tracts and make toxins. The source of infant botulism may be honey, but it's more likely to be exposure to soil contaminated with the bacteria.
Be sure to use proper techniques when canning foods at home to ensure that any botulism germs in the food are destroyed:
To reduce the risk of infant botulism, avoid giving honey — even a tiny taste — to children under the age of 1 year.
To prevent wound botulism and other serious bloodborne diseases, never inject or inhale street drugs.
For cases of foodborne botulism, doctors sometimes clear out the digestive system by inducing vomiting and giving medications to induce bowel movements. If you have botulism in a wound, a doctor may need to remove infected tissue surgically.
If you're diagnosed early with foodborne or wound botulism, injected antitoxin reduces the risk of complications. The antitoxin attaches itself to toxin that's still circulating in your bloodstream and keeps it from harming your nerves.
The antitoxin cannot, however, reverse the damage that's been done. Fortunately, nerves do regenerate. Many people recover fully, but it may take months and extended rehabilitation therapy.
A different type of antitoxin, known as botulism immune globulin, is used to treat infants.
Antibiotics are recommended for the treatment of wound botulism. However, these medications are not advised for other types of botulism because they can speed up the release of toxins.
If you're having trouble breathing, you'll probably need a mechanical ventilator for as long as several weeks as the effects of the toxin gradually lessen. The ventilator forces air into your lungs through a tube inserted in your airway through your nose or mouth.
As you recover, you may also need therapy to improve your speech, swallowing and other functions affected by the disease.