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Primary biliary cirrhosis - Generics

Primary biliary cholangitis (PBC), previously known as primary biliary cirrhosis, is a chronic liver disease characterized by the inflammation and destruction of the small bile ducts in the liver. This can eventually lead to scarring and damage to liver tissue, known as cirrhosis.

The cause of PBC is not fully understood, but it is believed to be an autoimmune disorder, where the body's immune system mistakenly attacks and damages the bile ducts in the liver. PBC is more common in women than men, and usually affects people over the age of 40.

Symptoms of PBC may include fatigue, itching, abdominal pain, jaundice, and fluid accumulation in the legs and abdomen. In some cases, PBC may be asymptomatic, and may only be detected through routine blood tests or imaging studies.

Treatment for PBC aims to slow the progression of the disease and manage symptoms. This may include medications to reduce inflammation and slow the damage to the liver, as well as medications to manage symptoms such as itching or fatigue. In some cases, liver transplant may be necessary if the liver becomes severely damaged.

It is important to seek medical attention if you are experiencing symptoms of PBC or have been diagnosed with the condition. Your healthcare provider can help determine the appropriate course of treatment and help monitor your liver function to prevent complications.


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