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Primary amoebic meningoencephalitis Generics
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Amphotericin B (Liposomal)
Dermatological Preparations
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Doxycycline
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Ketoconazole
Antimicrobial Drugs

Primary amoebic meningoencephalitis - Generics

Primary amoebic meningoencephalitis (PAM) is a rare but serious disease caused by the Naegleria fowleri amoeba, which is commonly found in warm freshwater, soil, and poorly maintained swimming pools and hot tubs. PAM affects the brain and spinal cord, and is usually fatal.

The disease is contracted when contaminated water enters the nose and the amoeba migrates to the brain, where it causes inflammation and destruction of brain tissue. Symptoms of PAM usually begin one to nine days after exposure and may include headache, fever, nausea, vomiting, stiff neck, confusion, seizures, and hallucinations.

Diagnosis of PAM is based on clinical symptoms, as well as laboratory tests and brain imaging studies. Treatment for PAM typically involves a combination of supportive care and medications, including antifungal drugs and antibiotics, as well as the use of specialized treatments such as hyperbaric oxygen therapy.

Prevention of PAM involves avoiding exposure to contaminated water, especially warm freshwater sources such as lakes, rivers, and hot springs. Wearing nose clips or keeping your head above water when swimming or diving in freshwater can also help to reduce the risk of infection.

If you experience symptoms of PAM or are concerned about your risk of infection, it is important to seek medical attention from a healthcare provider as soon as possible. Early diagnosis and treatment can improve the chances of recovery from this serious and potentially fatal disease.


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