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Non-ulcer dyspepsia, also known as functional dyspepsia, is a condition characterized by persistent or recurrent pain or discomfort in the upper abdomen, without evidence of an underlying ulcer or other digestive disorder. The exact cause of non-ulcer dyspepsia is not well understood, but it is believed to be related to a disturbance in the function of the stomach and small intestine.
Symptoms of non-ulcer dyspepsia can include:
Diagnosis of non-ulcer dyspepsia is made by ruling out other digestive disorders such as ulcers, gastroesophageal reflux disease (GERD), and inflammatory bowel disease (IBD). This may involve a combination of diagnostic tests, including endoscopy, stool tests, and blood tests.
Treatment of non-ulcer dyspepsia may involve lifestyle modifications such as avoiding foods that trigger symptoms, eating smaller and more frequent meals, and avoiding eating before bedtime. In some cases, medications such as acid-reducing drugs, prokinetic agents, and antidepressants may be used to help manage symptoms. Stress management techniques such as cognitive-behavioral therapy or relaxation techniques may also be helpful in managing symptoms.