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Drug-induced extrapyramidal syndrome - Generics

Drug-induced extrapyramidal syndrome (EPS) is a potential side effect of certain medications, including antipsychotic medications and some antiemetic medications. EPS refers to a group of movement disorders that are caused by the drugs affecting the extrapyramidal system in the brain, which controls movement.

Symptoms of EPS can include:

  1. Parkinsonism: slow movement, muscle stiffness, tremors, and a shuffling gait.
  2. Acute dystonia: sudden onset of muscle spasms and contractions, especially of the face, neck, tongue, or jaw.
  3. Akathisia: a feeling of restlessness and inability to sit still.
  4. Tardive dyskinesia: involuntary movements of the face, lips, tongue, and limbs that can develop after prolonged use of certain medications.

The risk of developing EPS can be minimized by using the lowest effective dose of the medication for the shortest period of time necessary. Treatment of EPS usually involves discontinuation or reduction of the medication causing the symptoms, and the use of medications to manage the symptoms.

There are several medications that can be used to manage EPS, including:

  1. Anticholinergic medications: used to treat acute dystonia and parkinsonism.
  2. Benzodiazepines: used to treat akathisia.
  3. Beta blockers: used to treat tremors and other symptoms of EPS.

It is important to talk to your healthcare provider if you experience any symptoms of EPS, especially if you are taking medications that can cause this condition. They can help determine the cause of the symptoms and develop a treatment plan to manage them.


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