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Osimertinib Brands
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Osimertinib - Brands
Osimertinib is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) that binds to certain mutant forms of EGFR (T790M, L858R, and exon 19 deletion) that predominate in non-small cell lung cancer (NSCLC) tumours following treatment with first-line EGFR-TKIs. As a third-generation tyrosine kinase inhibitor, osimertinib is specific for the gate-keeper T790M mutation which increases ATP binding activity to EGFR and results in poor prognosis for late-stage disease. Furthermore, osimertinib has been shown to spare wild-type EGFR during therapy, thereby reducing non-specific binding and limiting toxicity.
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Dermatological preparations
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Anidulafungin
Gastrointestinal System Drugs
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Emblic Myrobalan + Sesame
Herbal and Nutraceuticals
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Saccharin Sodium
Vitamin, Mineral & Nutritional Deficiency
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Eslicarbazepine Acetate
Central Nervous System Drugs
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Verteporfin
Eye preparations
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