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Osimertinib Brands
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Osimertinib - Brands
Osimertinib is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) that binds to certain mutant forms of EGFR (T790M, L858R, and exon 19 deletion) that predominate in non-small cell lung cancer (NSCLC) tumours following treatment with first-line EGFR-TKIs. As a third-generation tyrosine kinase inhibitor, osimertinib is specific for the gate-keeper T790M mutation which increases ATP binding activity to EGFR and results in poor prognosis for late-stage disease. Furthermore, osimertinib has been shown to spare wild-type EGFR during therapy, thereby reducing non-specific binding and limiting toxicity.
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Citric Acid Monohydrate
Respiratory System Drugs
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Herbal and Nutraceuticals
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Upadacitinib
Musculoskeletal systems
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N/A
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Allylestrenol
Endocrine & Metabolic System Drugs
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Lidocaine + Adrenaline
Anesthetics & Neuromuscular Blocking Drugs
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Mannitol
Cardiovascular System Drugs
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Cardiovascular system drugs
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