“May all be happy, may all be healed, may all be at peace and may no one ever suffer."
MUPS is abbreviation for Multiple-Unit Pellet System. However, from pharmaceutical industry and research perspective, the term in general refers to MUPS compacted into tablets. Thus, the resulting tablets prepared by compaction of modified release coated multiparticulates or pellets are called as MUPS. It is the more recent and challenging technology that combines the advantages of both tablets and pellet-filled capsules in one dosage form.
Clinical advantage of omeprazole MUPS tablet compared to conventional modified-release omeprazole tablets and pellet-filled omeprazole capsules:
Pharmacodynamic advantage:
Each film coated MUPS tablet contains Omeprazole enteric-coated micro pellets equivalent to Omeprazole 20 mg.
Omeprazole MUPS tablet is indicated in-
Adult:
Children over 2 years old:
Administration
Omeprazole is contraindicated in those patients who have known hypersensitivity to any other components of the formulation.
Omeprazole tablet should be used carefully if the patient has severe liver dysfunction and severe renal impairment.
Pregnancy & Lactation
Not known to be harmful. Omeprazole can be used during pregnancy. Omeprazole is excreted in breast milk but is not likely to influence the child when therapeutic doses are used.