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Clindamycin + Benzoyl peroxide

1.2% + 0.025%
Benzoyl peroxide, Azelaic acid & other preparations
0.00 (0)


Action Period: ...

Clindamycin is a semi-synthetic derivative of lincomycin. It inhibits bacterial protein synthesis by reversibly binding to the 50S ribosomal subunits thus blocking the transpeptidation or translocation reactions of susceptible organisms.

Benzoyl peroxide has mild keratolytic effect and antimicrobial activity which is attributed to its potent oxidizing activity. Clindamycin and Benzoyl peroxide are both active against Propionibacterium acnes, an organism associated with acne vulgaris.


Generic for Diseases

Generic Indications
  • Acne

Complement Generics
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Inimical Generics

Component

Drug Indications

Indicated in acne vulgaris.


Dosage Administration

Apply to the affected areas once or twice daily (morning and evening) after the skin is gently washed and patted dry.


Contraindication

Hypersensitivity to Clindamycin, lincomycin, benzoyl peroxide, or any component of the formulation; history of regional enteritis, ulcerative colitis, pseudomembranous colitis or antibiotic-associated colitis.


Side Effect

Application site pain, Application site exfoliation, Application site irritation, Erythema, Burning, Pruritus, Sunburn, Scaling, Drynes, Colitis, Peelin.


Precaution Warning

Avoid contact with mouth, eyes, lips & mucous membranes; abraded or eczematous skin. May discolor hair & dyed fabrics. Pregnancy & lactation.

Pregnancy & Lactation

Pregnancy Category- C. Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Lactation: Excretion in milk is unknown/ not recommended





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Clindamycin + Benzoyl peroxide

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