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Methylprednisolone Brands
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Methipred 8mg
General Pharmaceuticals Ltd.
Tablet Tablet
Size: 30 | Price: 300.90
Melpred 8mg
Pharmasia Limited
Tablet Tablet
Size: 30 | Price: 300.00
Depomed 2mg
Drug International Ltd.
Tablet Tablet
Size: 50 | Price: 150.00
Depodrol 8mg
Opsonin Pharma Ltd.
Tablet Tablet
Size: 30 | Price: 300.00
Medrol 16mg
Janata Traders
Tablet Tablet
Size: 14 | Price: 328.00
Melpred 4mg
Pharmasia Limited
Tablet Tablet
Size: 30 | Price: 150.00
Mepcort 4mg
Globe Pharmaceuticals Ltd.
Tablet Tablet
Size: 30 | Price: 150.00
Methigic 16mg
Square Pharmaceuticals Ltd.
Tablet Tablet
Size: 20 | Price: 410.00
Prednisolone 5mg
Ambee Pharmaceuticals Ltd.
Tablet Tablet
Size: 200 | Price: 239.85
Solupred 2mg
Ziska Pharmaceuticals Ltd.
Tablet Tablet
Size: 50 | Price: 150.00
Methigic 2mg
Square Pharmaceuticals Ltd.
Tablet Tablet
Size: 50 | Price: 150.00
Depomed 16mg
Drug International Ltd.
Tablet Tablet
Size: 10 | Price: 200.00
Solupred 4mg
Ziska Pharmaceuticals Ltd.
Tablet Tablet
Size: 50 | Price: 250.00
Predixa 8mg
UniMed UniHealth
Tablet Tablet
Size: 20 | Price: 240.00
Solupred 16mg
Ziska Pharmaceuticals Ltd.
Tablet Tablet
Size: 10 | Price: 150.00
Depodrol 2mg
Opsonin Pharma Ltd.
Tablet Tablet
Size: 50 | Price: 150.00
Depomed 8mg
Drug International Ltd.
Tablet Tablet
Size: 20 | Price: 200.00
Predixa 4mg
UniMed UniHealth
Tablet Tablet
Size: 30 | Price: 180.00

Methylprednisolone - Brands

Methylprednisolone is a potent anti-inflammatory steroid. It has greater anti-inflammatory potency than Prednisolone, even less tendency than prednisolone to induce sodium and water retention. The relative potency of Methylprednisolone to Hydrocortisone is at least four to one.

Pharmacology

Pharmacodynamic properties: Methylprednisolone Is a potent anti-inflammatory agent with the capacity to profoundly inhibit the immune system. Glucocorticoids primarily bind to and activate intracellular glucocorticoid receptors that being activated bind to promoter regions of DMA (which may activate or suppress transcription) and activate transcription factors that result in inactivation of genes through deacetylation of histones. Methylprednisolone influences the kidney and fluid & electrolyte balance, lipid,

protein, and carbohydrate metabolism, skeletal muscle, the cardiovascular system, the immune system, the nervous system, and the endocrine system.

Pharmacokinetic properties: The absolute bioavailability of Methylprednisclone is generally high (82% to 89%) following oral administration and rapidly absorbed and the maximum plasma concentration is achieved around 1.5 to 2.3 hours across doses following oral administration in normal healthy adults. Methylprednisolone is widely distributed into the tissues and its volume of distribution is 41-61.5 liter. It crosses the Wood-brain barrier and the placental barrier and is secreted in breast milk. The plasma protein binding of Methylprednisolone in humans is approximately 77%. Methylprednisolone is metabolized in the liver to inactive metabolites. No dosing adjustments are necessary for renal failure. Methylprednisolone is haemodializable.


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