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Hydrochlorothiazide + Triamterene Brands
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G-Thiazide T 25mg + 50mg
Gonoshasthaya Pharma Ltd.
Tablet Tablet
Size: 100 | Price: 52.00
Dezide 25mg + 50mg
Eskayef Pharmaceuticals Ltd.
Tablet Tablet
Size: 100 | Price: 100.00

Hydrochlorothiazide + Triamterene - Brands

Triamterene directly inhibits the exchange of Na for K and hydrogen in the distal renal tubule. Hydrochlorothiazide increases the excretion of Na and Cl ions, and consequently of water, by reducing electrolyte reabsorption from the renal tubules.

Hydrochlorothiazide is a thiazide diuretic. Thiazides affect the renal tubular mechanisms of electrolyte reabsorption, directly increasing excretion of sodium and chloride in approximately equivalent amounts. Indirectly, the diuretic action of Hydrochlorothiazide reduces plasma volume, with consequent increases in plasma renin activity, increases in aldosterone secretion, increases in urinary potassium loss, and decreases in serum potassium. The renin-aldosterone link is mediated by angiotensin II, so co-administration of anangiotensin converting enzyme (ACE) inhibitor tends to reverse the potassium loss associated with these diuretics.


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