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Esomeprazole (MUPS tablet) - Brands
MUPS is abbreviation for Multiple Unit Pellet System. However, from pharmaceutical industry and research perspective, the term in general refers to MUPS compacted into tablets. It is a pharmaceutical solid dosage form produced by compressing a mixture of drug-containing pellets and powder excipients. MUPS is one of the more recent and challenging technologies that combine the advantages of both tablets and pellet-filled capsules in one dosage form.
Pharmacology
Esomeprazole is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of the H+/K+ ATPase in the gastric parietal cell. Esomeprazole (S-isomer of omeprazole) is the first single optical isomer of proton pump inhibitor, provides better acid control than racemic proton pump inhibitors.
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