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One Pharma Ltd.
Neobastin 10mg
Generic for Diseases
- Allergic conditions
- Allergic rhinitis
- Rhinitis
- Urticaria
Ebastine is a long-acting and selective H1-histamine receptor antagonist. After repeated administration, inhibition of peripheral receptors remains at a constant level. Ebastine is rapidly absorbed and undergoes extensive first-pass metabolism following oral administration. Ebastine is almost totally converted to the pharmacologically active acid metabolite, carebastine.
Ebastine is indicated for the symptomatic treatment of:
- Seasonal and Perennial Allergic Rhinitis.
- Chronic Idiopathic Urticaria.
Tablet:
- Adults (more than 12 years of age): 10 mg (one tablet) once daily.
- Children (6-12 years of age): 5 mg (half tablet) once daily.
Syrup:
- Children (2-5 years of age): 2.5 ml once daily (upto 5 ml in severe cases such as Perennial Allergic Rhinitis).
- Children (6-12 years of age): 5 ml once daily (upto 10 ml in severe cases such as Perennial Allergic Rhinitis).
Ebastine may be taken with or without food.
Patients with a known hypersensitivity to Ebastine or any of its ingredients.
The most common side-effects are headache, dry mouth and drowsiness. Less commonly reported side effects include abdominal pain, dyspepsia, nausea and insomnia.
Overdose Effects
No clinically meaningful signs or symptoms were observed up to 100 mg given once daily. There is no specific antidote for Ebastine. In case of accidental overdoses, gastric lavage, monitoring of vital functions including ECG and symptomatic treatment should be carried out.
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