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Incepta Pharmaceuticals Ltd.

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Incepta Pharmaceuticals Ltd.
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Urikal (1500mg + 250mg) / 5ml

Size: 100 ml bottle Price: 120.00
Oral Solution Oral Solution
Potassium Citrate + Citric Acid
Prevention of repeated kidney stone formation, Urinary Alkalinizing Agent
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Alternate Strengths


Generic for Diseases

Generic Indications

Generic Description

Potassium Citrate and Citric Acid oral solution is a stable and pleasant-tasting oral systemic alkalizer. Potassium Citrate is absorbed and metabolized to Potassium Bicarbonate, thus acting as a systemic alkalizer. This product alkalinizes the urine without producing a systemic alkalosis in recommended doses. It is highly palatable, pleasant tasting and tolerable, even when administered for long periods. Potassium Citrate does not neutralize the gastric juice or disturb digestion.


Component

Drug Indication

This preparation is indicated in the following cases:

  • To relieve discomfort in urinary tract infections
  • To prevent kidney stone
  • With uricosuric agent to prevent gout
  • Acidosis caused by kidney diseases

Dosage Administration

To relieve discomfort in UTI:

  • Adults and children over 6 years: 10 ml 3 times daily, diluted with 1 glass of water.
  • Children 1-6 years: 5 ml 3 times daily, diluted with ½ glass of water.

To prevent kidney stones, With a uricosuric agent to prevent gout, Acidosis caused by kidney diseases:

  • Adults: 10-15 ml 4 times daily (or as directed by the physician) diluted with 1 glass of water.
  • Pediatric: 5-10 ml 4 times daily (or as directed by the physician) diluted with ½ glass of water.

Contraindication

The drug is contraindicated in severe renal impairment with oliguria or azotemia, untreated Addison's disease, acute dehydration, severe myocardial damage and hyperkalemia from any cause.


Side Effect

This solution is generally well tolerated without any unpleasant side effect when given in recommended doses to patients with normal renal function and urinary output. However, as with any alkalinizing agent, caution must be used in certain patients with abnormal renal mechanisms to avoid development of hyperkalemia or alkalosis. Potassium intoxication causes listlessness, weakness, mental confusion, tingling of extremities and other symptoms associated with a high concentration of Potassium in the serum.

Overdose Effects

The administration of oral Potassium salts to persons with normal excretory mechanisms for potassium rarely causes serious hyperkalemia. However, if excretory mechanisms are impaired, hyperkalemia can result. Hyperkalemia, when detected, must be treated immediately because lethal levels can be reached in a few hours. If hyperkalemia occurs, treatment measures will include the followings: (1) Elimination of foods or medications containing potassium. (2) The intravenous administration of 300 to 500 ml/hr of dextrose solution (10 to 25%), containing 10 units of insulin/20 gm dextrose. (3) The use of exchange resins, hemodialysis or peritoneal dialysis.


Precaution Warning

Precautions & Warnings

The solution should be used with caution in patients with low urinary output. It should be diluted adequately with water to minimize the possibility of gastrointestinal injury associated with the oral ingestion of concentrated Potassium salt preparations; and preferably, to take each dose after meals. Large doses may cause hyperkalemia and alkalosis, especially in the presence of renal disease.

Pregnancy & Lactation

No information is available regarding the use of this drug during pregnancy and lactation.





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