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Eskayef Pharmaceuticals Ltd.

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Eskayef Pharmaceuticals Ltd.
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Dorenta 50mg

Size: 50 Price: 125.00
Tablet Tablet
Diphenhydramine Hydrochloride
Sedating Anti-histamine
0.00 (0)



Alternate Strengths


Generic for Diseases
  • Hives (Cold urticaria)
  • Allergies

Generic Indications
  • Allergic conditions
  • Allergic rhinitis
  • Allergies
  • Chickenpox
  • Chronic urticaria
  • Common cold
  • Extrapyramidal symptoms
  • Insect bites
  • Insect stings
  • Insomnia
  • Motion sickness
  • Perennial or seasonal allergic rhinitis
  • Pregnancy-associated nausea and vomiting
  • Prolonged vomiting
  • Rhinitis
  • Rhinorrhoea
  • Serum sickness
  • Stings
  • Transfusion reactions
  • Vestibular neuritis
  • Wheezing

Generic Description

Diphenhydramine is an antihistamine with anticholinergic and sedative effects. It competes with histamine for H1-receptor sites on effector cells in the GI tract, blood vessels and respiratory tract.


Component

Drug Indication

Diphenhydramine is indicated for the treatment of followings:

  • Seasonal, perennial, vasomotor rhinitis
  • Urticaria, angioneurotic oedema, anaphylaxis
  • Pruiritic conditions
  • Premedication for emesis and motion sickness
  • Miscellaneous like meniere's disease and parkinsonism

Dosage Administration

Adult-

  • Most allergic conditions: 25-50 mg three times a day with a further 50 mg at night.

Children-

  • 1 to 5 years of age: 5 mg i.e., 2.5 ml of elixir 4 times a day
  • More than 6 years of age: 10 mg i.e. 5 ml of elixir 4 times a day

Contraindication

Known hypersensitivity to Diphenhydramine Hydrochloride, Ammonium chloride is contra-indicated in presence of impaired hepatic or renal function.


Side Effect

Side effect includes sedation, dizziness, tinnitus, fatigue, ataxia, blurred vision, diplopia, euphoria, and epigastric discomfort.

Overdose Effects

Symptoms: Impaired consciousness; psychosis, seizures, antimuscarinic symptoms (e.g. mydriasis, tachycardia, tachyarrhythmias), resp failure, rhabdomyolysis; acute delirium with visual and auditory hallucination (topical).


Precaution Warning

Caution should be exercised with patients in whom drowsiness is undesirable e.g., drivers, machine operators. Concomitant consumption of alcohol or central nervous system (CNS) depressants will potentiate drowsiness.

Pregnancy & Lactation

Category B: There are no adequate and well controlled studies in pregnant women using diphenhydramine hydrochloride. Therefore, diphenhydramine hydrochloride should be used in pregnancy only if clearly needed. Diphenhydramine hydrochloride has been reported to be excreted in breast milk and thus, use of diphenhydramine hydrochloride in lactating mother is not recommended.





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