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Delta Pharma Ltd.

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Pyrenol 500mg + 65mg

Size: 200 Price: 400.00

Tablet

Paracetamol + Caffeine

Non opioid analgesics

0.00 (0)

102 Alternate Brands

Alternate Strengths

500mg + 65mg

Generic for Diseases

Generic Indications

Acute migraine attacks
Back pain
Bodyache
Cold
Dysmenorrhoea
Fever
Flu
Headache
Influenza
Migraine
Pain
Rheumatic pain
Sore throat
Toothache

Generic Description

This is a combination of Paracetamol and Caffeine. Paracetamol has analgesic and antipyretic properties with weak anti-inflammatory activity. Caffeine is an alkaloid which is a theophylline-like xanthine derivative. By intermolecular association with Paracetamol, Caffeine increases the solubility and transmembrane permeation of Paracetamol. In addition, Caffeine increases the pain threshold and tolerance of pain. Caffeine has also an intrinsic power to raise vessel tone in the brain, which provides another benefit to treat migraine and headache.

Component

Drug Indication

The is indicated in the following condition-

Headache
Migraine
Toothache
Neuralgia
Feverishness
Period pain
Sore throat
Backache
Help to reduce the temperature
Aches and pain of colds and flu

Dosage Administration

Adult dose: 1-2 tablets every 4-6 hours. Maximum dose: 8 tablets daily.

Child dose: Not recommended for children below 12 years.

Contraindication

Paracetamol is contraindicated in patients with severe renal function impairment and hepatic disease (Viral Hepatitis). Known hypersensitivity to paracetamol or caffeine.

Side Effect

Side effects of paracetamol are usually mild, though haematological reactions including thrombocytopenia, leukopenia, pancytopenia, neutropenia, and agranulocytosis have been reported. Pancreatitis, skin rashes, and other allergic reactions occur occasionally.

Overdose Effects

Symptoms of Paracetamol overdose in the first 24 hours are pallor, nausea, vomiting, anorexia and abdominal pain. Liver damage may become apparent 12 to 40 hours after ingestion. Abnormalities of glucose metabolism and metabolic acidosis may occur.

Precaution Warning

Paracetamol & Caffeine should be given cautiously in the following cases: In patients with hepatic or renal failure, in patients taking other hepatotoxic medication. Prolonged use of the drug without consulting a physician should be avoided.