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Extrapyramidal symptoms Generics
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Extrapyramidal symptoms - Generics

Extrapyramidal symptoms (EPS) are a group of side effects that can occur as a result of taking certain medications, most commonly antipsychotic medications. These symptoms affect the motor system and can include:

  1. Parkinsonism: This refers to symptoms similar to Parkinson's disease, such as rigidity, tremors, bradykinesia (slowness of movement), and postural instability.
  2. Akathisia: This is a feeling of restlessness, agitation, or discomfort that makes a person unable to stay still.
  3. Dystonia: This is a condition characterized by involuntary muscle contractions that cause repetitive or twisting movements or abnormal postures.
  4. Tardive dyskinesia: This is a potentially irreversible disorder characterized by repetitive, involuntary, and purposeless movements, such as lip smacking, tongue protrusion, or rapid eye blinking.

EPS occur due to an imbalance of neurotransmitters in the brain, particularly dopamine. Antipsychotic medications work by blocking dopamine receptors, which can lead to an excess of dopamine in certain areas of the brain, resulting in EPS.

The risk of EPS can vary depending on the type of antipsychotic medication, the dose, and the individual patient's sensitivity to the medication. Other factors that can increase the risk of EPS include age, female gender, and a history of neurological or movement disorders.

If a person experiences EPS while taking antipsychotic medication, it is important to report the symptoms to a healthcare provider. Treatment options may include adjusting the dose or switching to a different medication. In some cases, medications such as anticholinergics or benzodiazepines may be used to manage the symptoms of EPS.


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