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Sodium Picosulfate + Magnesium Oxide + Citric Acid - Brands
Sodium Picosulfate is hydrolyzed by colonic bacteria to form an active metabolite: bis-(p-hydroxy-phenyl)-pyridyl-2-methane, BHPM, which acts directly on the colonic mucosa to stimulate colonic peristalsis. Magnesium oxide and citric acid react to create magnesium citrate in solution, which is an osmotic agent that causes water to be retained within the gastrointestinal tract. The stimulant laxative activity of Sodium Picosulfate together with the osmotic laxative activity of Magnesium Citrate produces a purgative effect which, when ingested with additional fluids, produces watery diarrhea. Sodium Picosulfate, which is a prodrug, is converted to its active metabolite, BHPM, by colonic bacteria
Sodium picosulfate, magnesium oxide, and anhydrous citric acid is used in adults to empty the colon (large intestine, bowel) before a colonoscopy (examination of the inside of the colon to check for colon cancer and other abnormalities) so that the doctor will have a clear view of the walls of the colon. Sodium picosulfate, magnesium oxide, and anhydrous citric acid is also used in children 9 years of age and older to empty the colon (large intestine, bowel) before a colonoscopy.
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