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Repaglinide - Brands
Repaglinide is an oral blood-glucose-lowering drug of the meglitinide class used in the management of Type 2 diabetes mellitus (NIDDM). Repaglinide works by causing pancreas to release more insulin into the blood stream which possesses rapid onset of action and rapid elimination.
Pharmacology
Repaglinide binds to specific receptors in the cell membrane leading to the closure of ATP dependent K+ channels and the depolarisation of cell membrane. This in turn, leads to Ca++ influx, increased intracellular Ca++ and the stimulation of insulin secretion.
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