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Oxytetracycline is primarily a bacteriostatic broad-spectrum antibiotic, which has a wide spectrum of activity against Gram-positive and Gram-negative microorganisms. Usually Oxytetracycline acts as an antimicrobial agent by inhibiting the protein synthesis of bacteria. It is also very effective against parasites such as rickettsia, mycoplasma, chlamydia and amoeba etc.
Pharmacology
Oxytetracycline inhibits cell growth by inhibiting translation. It binds to the 30S ribosomal subunit and prevents the amino-acyl tRNA from binding to the A site of the ribosome. The binding is reversible in nature. Oxytetracycline is lipophilic and can easily pass through the cell membrane or passively diffuses through porin channels in the bacterial membrane.