welcome Welcome

“May all be happy, may all be healed, may all be at peace and may no one ever suffer."


Loading...
Nilotinib Brands
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z
Tasigna 200mg
Novartis (Bangladesh) Ltd.
Capsule Capsule
Size: 28 | Price: 85441.90
Niloren 200mg
Renata Limited
Capsule Capsule
Size: 12 | Price: 9600.00

Nilotinib - Brands

Pazopanib is a multi-tyrosine kinase inhibitor of vascular endothelial growth factor receptor (VEGFR)-1, VEGFR-2, VEGFR-3, platelet-derived growth factor receptor (PDGFR) and fibroblast growth factor receptor (FGFR)-1 and -3, cytokine receptor (Kit), interleukin-2 receptor-inducible T- cell kinase (Itk), lymphocyte-specific protein tyrosine kinase (Lck), and transmembrane glycoprotein receptor tyrosine kinase (c-Fms). In vitro, Pazopanib inhibited ligand-induced autophosphorylation of VEGFR-2, Kit, and PDGFR receptors.

Absorption: Pazopanib is absorbed orally with the median time to achieve peak concentrations of 2 to 4 hours after the dose. Daily dosing at 800 mg results in geometric mean AUC and Cmax of 1,037 mcg/mL and 58.1 mcg/mL (equivalent to 132 μM), respectively. There was no consistent increase in AUC or Cmax at Pazopanib doses above 800 mg.

Distribution: Binding of Pazopanib to human plasma protein in vivo was greater than 99% with no concentration dependence over the range of 10 to 100 mcg/mL. In vitro, studies suggest that Pazopanib is a substrate for P-gp and BCRP.

Metabolism: In vitro studies demonstrated that Pazopanib is metabolized by CYP3A4 with a minor contribution from CYP1A2 and CYP2C8.

Elimination: Pazopanib has a mean half-life of 30.9 hours after administration of the recommended dose of 800 mg. Elimination is primarily via feces with renal elimination accounting for less than 4% of the administered dose.


...
Diphenhydramine + Dextrom...
Respiratory System Drugs
...
Verapamil Hydrochloride
Cerebrovascular system drugs
...
Saribadyarista
Herbal and Nutraceuticals
...
Orlistat
Central Nervous System Drugs
...
Sodium Dihydrogen Phospha...
Sodium Dihydrogen + Disodium Hydrogen Phosphate
...
Ciprofloxacin
Antimicrobial drugs
...
Tinidazole
Antimicrobial Drugs
...
Letrozole
Chemotherapy & Immunosuppressants

Bangladesh is Number One in Digital Medical Management.
To be happy, beautiful, healthy, wealthy, hale and long-lived stay with DM3S.