This cream is a combination of Neomycin, Polymyxin B and Pramoxine HCl. Neomycin is bactericidal for many gram-positive and gram-negative organisms. It is an aminoglycoside antibiotic that inhibits protein synthesis by binding with ribosomal RNA and causing misreading of the bacterial genetic code. Polymyxin B is bactericidal for a variety of gram-negative organisms. It increases the permeability of the bacterial cell membrane by interacting with the phospholipids components of the membrane. Pramoxine is an external analgesic that provides temporary relief of pain or discomfort.

This is a first aid cream. It prevents infections and provides temporary relief of pain or discomfort in minor cuts, scrapes and burns.

Clean the affected area. Apply a small amount of product (an amount equal to the surface area of the tip of a finger). May be covered with a sterile bandage. Safety and effectiveness in children below 2 years of age have not been established.

Neomycin, Polymyxin B and Pramoxine HCl cream should not be administered to individuals who are hypersensitive to Neomycin, Polymyxin B, Pramoxine or any other components of this product.

Topical antibiotics, particularly Neomycin sulphate, may cause cutaneous sensitization. The manifestations of sensitization to topical antibiotics are usually itching and reddening. When used in small doses, no common side effects have been reported with this product.

Do not use this medication in the eyes or apply to large areas of the body. Do not use longer than one week unless directed by the physician.

Pregnancy & Lactation

Use Neomycin, Polymyxin B and Pramoxine HCl during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether this drug is excreted in breast milk. Exercise caution when applying Nepranol to a nursing mother.