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Lidocaine Hydrochloride (Jelly) Brands
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Xylogel 2%
UniMed UniHealth
Gel Gel
Size: 30 gm tube | Price: 100.00
Z-Lidocaine 2%
Ziska Pharmaceuticals Ltd.
Gel Gel
Size: 30 gm tube | Price: 90.00
Jasocaine 2%
Jayson Pharmaceuticals Ltd.
Gel Gel
Size: 5 gm tube | Price: 18.00

Lidocaine Hydrochloride (Jelly) - Brands

This Jelly is a sterile local anaesthetic product which contains Lidocaine Hydrochloride USP in a water-soluble Jelly base. It is used for topical/surface anaesthesia. The onset of action is 3-5 minutes. It may be rapidly and almost completely absorbed following topical application to mucous membrane and systemic effects may occur.

Pharmacology

Lidocaine acts mainly by inhibiting sodium influx through sodium specific ion channels in the neuronal cell membrane, in particular the so called voltage-gated sodium channels. When the influx of sodium is interrupted, an action potential cannot arise and signal conduction is inhibited. The receptor site is thought to be located at the cytoplasmic (inner) portion of the sodium channel. Lidocaine binds more readily to sodium channels in activated state, thus onset of neuronal blockade is faster in neurons that are rapidly firing. This is referred to as state dependent blockade.


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