Hydroxypropyl Methylcellulose is a non pyrogenic viscoelastic solution that occupies space and protects tissue. When used in anterior segment surgeries, it allows for more efficient manipulation with less trauma to the ocular tissues, such as the corneal endothelium, by maintaining a deep chamber. The viscoelastic properties of Hydroxypropyl methylcellulose facilitate pushing back the vitreous face, which prevents the formation of a postoperative flat chamber.

Hydroxypropyl Methylcellulose is indicated as a surgical aid (medical device) during surgicalprocedures involving the anterior chamber of the eye, including extraction of the lens and insertion of intra-ocular lenses. It maintains the depth of the anterior chamber during the whole surgical procedure and permits greater operative precision without the risk of damaging the endothelium of the cornea or other intra-ocular tissues.

Each pre-filled syringe is for single intraocular use only. The quantity injected into the anterior chamber of the eye must be adjusted according to the volume of the aqueous humour and the anatomical structure to be protected.

At present, there are no known contraindications to the use of Hydroxypropyl Methylcellulose when used as recommended.

Hydroxypropyl Methylcellulose has been extremely well tolerated after injection into the human eye. A transient rise in intraocular pressure postoperatively has been reported in some cases. Rarely, postoperative inflammatory reactions (iritis, hypopyon), as well as incidents of corneal edema and corneal decompensation, have been reported with viscoelastic agents.

Overdose Effects

Mechanical blockage of drainage at the trabecular level may cause a transient increase in intraocular pressure after surgery.

Precautions are limited to those normally associated with the ophthalmic surgical procedure being performed. There may be transient increased intraocular pressure following surgery because of pre-existing glaucoma or due to the surgery itself. For these reasons, the following precautions should be considered. Hydroxypropyl Methylcellulose should be removed from the anterior chamber at the end of surgery. If the postoperative intraocular pressure increases above expected values, appropriate therapy should be administered.

Warning-

• For intraocular use only
• For single use only

Pregnancy & Lactation

Pregnancy: Hydroxypropyl Methylcellulose has not been shown to cause birth defects or other problems in humans.

Lactation: It has not been reported to cause problems in nursing babies.