“May all be happy, may all be healed, may all be at peace and may no one ever suffer."
Human Tetanus Immunoglobulin is a sterile solution containing human tetanus immunoglobulin which is prepared by Cohn fractionation of plasma of individuals with high titers of antibody to the tetanus antigen and heat inactivation step in manufacturing process (60°C, 10 hrs) is used to inactivate infectious agents such as Hepatitis B virus, Hepatitis C virus, Human immunodeficiency virus and so on.
Pharmacology
Human clostridium tetani toxoid immune globulin prevents tetanus toxoid from damaging tissue and producing the symptoms associated with tetanus. The immune globulin binds to tetanus toxiod, interfering with the normal interaction of the toxoid with human tissue. This prevents the toxoid from invading the nervous system and producing painful muscle spasms as well as autonomic dysfunction. The Clostridium tetani bacterium is killed either via antibiotic treatment of the host's immune system and immune globulin-bound toxoid is likely broken down by phagocytic immune cells.