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Pregnyl 5000IU / vial
Healthcare Pharmaceuticals Ltd.
Human Chorionic Gonadotrophin - Brands
Pharmacodynamic Properties: Highly Purified Human Chorionic Gonadotrophin has LH activity. LH is indispensable in normal female and male gamete growth and maturation, and gonadal steroid production.
- In the female: Human Chorionic Gonadotrophin is given as a substitute for the endogenous mid-cycle LH surge to induce the final phase of follicular maturation, leading to ovulation. Human Chorionic Gonadotrophin is also given as a substitute for endogenous LH during the luteal phase.
- In the male: Human Chorionic Gonadotrophin is given to stimulate Leydig cells to promote the production of testosterone.
Pharmacokinetic Properties: Maximal Human Chorionic Gonadotrophin plasma levels will be reached approximately six hours after a single injection of Human Chorionic Gonadotrophin . Human Chorionic Gonadotrophin is for approximately 80 percent metabolized, predominantly in the kidneys. Following intramuscular injection (IM) the apparent elimination half-life of Human Chorionic Gonadotrophin is about 2 days. On basis of the recommended dose regimens and elimination half-life, accumulation does not occur.
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