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Panodin SR 600mg
Square Pharmaceuticals Ltd.
Tablet (SR) Tablet (SR)
Size: 30 | Price: 453.00
Etogesic SR 600mg
ACME Laboratories Ltd.
Tablet (SR) Tablet (SR)
Size: 20 | Price: 300.80
Edopain 300mg
Incepta Pharmaceuticals Ltd.
Capsule Capsule
Size: 30 | Price: 240.00
Edopain ER 600mg
Incepta Pharmaceuticals Ltd.
Tablet (ER) Tablet (ER)
Size: 20 | Price: 360.00
Edolac 300mg
Opsonin Pharma Ltd.
Capsule Capsule
Size: 30 | Price: 240.90
Edolac ER 600mg
Opsonin Pharma Ltd.
Tablet (ER) Tablet (ER)
Size: 12 | Price: 216.84

Etodolac - Brands

Etodolac is a nonsteroidal anti-inflammatory drug (NSAID) that exhibits anti inflammatory, analgesic and antipyretic activities. The mechanism of action of Etodolac, like that of other NSAIDs related to prostaglandin synthesis inhibition

Pharmacology

Similar to other NSAIDs, the anti-inflammatory effects of etodolac result from inhibition of the enzyme cycooxygenase (COX). This decreases the synthesis of peripheral prostaglandins involved in mediating inflammation. Etodolac binds to the upper portion of the COX enzyme active site and prevents its substrate, arachidonic acid, from entering the active site. Etodolac was previously thought to be a non-selective COX inhibitor, but it is now known to be 5-50 times more selective for COX-2 than COX-1. Antipyresis may occur by central action on the hypothalamus, resulting in peripheral dilation, increased cutaneous blood flow, and subsequent heat loss.


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