“May all be happy, may all be healed, may all be at peace and may no one ever suffer."
Ceftibuten is the dihydrate salt of Ceftibuten, is a semi-synthetic Cephalosporin antibiotic for oral administration. Ceftibuten exerts its bactericidal action by binding to essential target proteins of the bacterial cell wall. This binding leads to inhibition of cell-wall synthesis.
Ceftibuten is indicated for the treatment of individuals with mild-to-moderate infections caused by susceptible strains of the designated microorganisms in the specific conditions listed below.
Otitis Media-
Tonsillitis/Pharyngitis-
Bronchitis-
Cystitis-
Pneumonia-
Sinusitis-
Urinary tract Infection-
Ceftibuten is contraindicated in patients with known allergy to the cephalosporin group of antibiotics.
Nausea, headache, diarrhea, dyspepsia, dizziness, abdominal pain, vomiting.
As with other broad-spectrum antibiotics, prolonged treatment may result in the possible emergence and overgrowth of resistant organisms. Careful observation of the patient is essential. The dose of Ceftibuten may require adjustment in patients with varying degrees of renal insufficiency. Ceftibuten should be prescribed with caution to individuals with a history of gastrointestinal disease, particularly colitis.
Renal Impairment-
Hepatic Impairment: Dose adjustment is not necessary.
Pregnancy & Lactation
Pregnancy Category B. There are no controlled data on the use of Ceftibuten in pregnant women. Ceftibuten should be used in pregnancy only when the benefit clearly outweighs the risk. It is not known whether Ceftibuten (recommended dosage) is excreted in human milk. Because many drugs are excreted in human milk, caution should be excercised when Ceftibuten is administered to nursing women.